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Small Molecule Detection and Sequestration
Nucleic Acid-based Treatment of Organophosphate Poisoning
Nucleic Acid-Based Treatment of Organophosphate Poisoning
Water Purification using Aptamer-Functionalized Membranes
Cellular Imaging using Quantum Dots and Aptamers
Nucleic Acid-Based Treatment of Organophosphate Poisoning
Relevant Publications
Romero-Reyes, M. A.; Heemstra, J. M. Small Molecule Sequestration Using Aptamer-Functionalized Membranes. ACS Materials Lett.; 2019
Tan, Z.; Heemstra, J. M. High-Throughput Small-Molecule Enantiopurity Measurement Using Flow Cytometry. ChemBioChem 2018 Accepted Article.
Tan, Z.; Feagin, T. A.; Heemstra, J. M. Temporal Control of Aptamer Biosensors Using Covalent Self-Caging to Shift Equilibrium. J. Am. Chem. Soc. 2016138, 6328-6331.
Meek, K. N.; Rangel, A. E.; Heemstra, J. M. Enhancing aptamer function via in vitro selection using modified nucleic acids. Methods 2016 29-36.
Perera, R. T.; Fleming, A. M.; Peterson, A. M.; Heemstra, J. M.; Burrows, C. J.; White, H. S. Size-dependent unzipping of duplexes of A-form DNA-RNA, A-form DNA-PNA, and B-form DNA-DNA in the alpha-hemolysin nanopore. Biophys. J. 2016110, 306-314
Heemstra, J. M. Learning from the Unexpected in Life and DNA Self-Assembly. Beil. J. Org. Chem. 2015 11, 2713-2720.
Peterson, A. M.; Jahnke, F. M.; Heemstra, J. M. Modulating the Substrate Selectivity of DNA Aptamers Using Surfactants. Langmuir 2015 31, 11769-11773.
Feagin, T. A.; Olsen, D. P. V.; Headman, Z. C.; Heemstra, J. M. High-Throughput Enantiopurity Analysis using Enantiomeric DNA-Based Sensors. J. Am. Chem. Soc. 2015 137, 4198-4206.
Peterson, A. M.; Heemstra, J. M. Controlling Self-Assembly of DNA-Polymer Conjugates for Applications in Imaging and Drug Delivery. WIREs Nanomed. Nanobiotechnol., 2015 7, 282-297.
Kent, A. D.; Spiropulos, N. G.; Heemstra, J. M. General Approach for Engineering Small-Molecule-Binding DNA Split Aptamers. Anal. Chem. 2013 85, 9916-9923.
Sharma, A. K.; Kent, A. D.; Heemstra, J. M. Enzyme-Linked Small-Molecule Detection using Split Aptamer Ligation. Anal. Chem. 2012 84, 6104-6109.
Sharma, A. K.; Heemstra, J. M. Small Molecule-Dependent Split Aptamer Ligation. J. Am. Chem. Soc. 2011 133, 12426-12429.
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